{"title":"TUDCA Supplements | Buy Tauroursodeoxycholic Acid 500mg | Charava","description":"\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eTUDCA (Tauroursodeoxycholic Acid)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eTUDCA is one of the most thoroughly researched bile acids in longevity and liver science. Charava's TUDCA delivers 500mg of pharmaceutical-grade tauroursodeoxycholic acid per capsule, vegan, GMP-certified, and free from fillers. Whether you're supporting liver health, cellular resilience, or a broader longevity stack, this is where to start.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eWhat is TUDCA?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eTUDCA stands for tauroursodeoxycholic acid, a water-soluble bile acid naturally synthesised in the liver from UDCA (ursodeoxycholic acid) and the amino acid taurine. Small amounts are produced endogenously, but therapeutic and longevity-focused supplementation typically requires doses of 250 to 1,000mg per day, well beyond what the body produces on its own.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eUnlike standard UDCA, a prescription medication used for liver conditions, TUDCA's taurine conjugation makes it significantly more hydrophilic and bioavailable. This improved solubility means it is better absorbed, more effective at low doses, and gentler on the gut. TUDCA is the preferred form for supplementation.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eWhat Does TUDCA Do?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eTUDCA acts on several interconnected biological pathways that are central to liver health, cellular function, and healthy ageing.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cem\u003eLiver protection.\u003c\/em\u003e TUDCA promotes healthy bile flow and protects hepatocytes (liver cells) from damage caused by toxic bile acid accumulation. It has been used clinically for cholestasis, a condition where bile flow from the liver is impaired, and has shown significant reductions in liver enzymes (ALT and AST) in controlled trials.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cem\u003eEndoplasmic reticulum (ER) stress relief.\u003c\/em\u003e The endoplasmic reticulum is responsible for folding proteins within cells. When proteins misfold due to toxins, metabolic stress, or ageing, ER stress occurs, driving inflammation, insulin resistance, and cell death. TUDCA acts as a chemical chaperone, stabilising proteins and dramatically reducing ER stress. This is one of the most significant mechanisms underpinning its effects on metabolic and neurological health.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cem\u003eMitochondrial support.\u003c\/em\u003e TUDCA preserves mitochondrial membrane integrity and inhibits the release of cytochrome c, a key trigger of cell death (apoptosis). Healthy mitochondria are fundamental to energy production, athletic performance, and cellular longevity.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cem\u003eNeuroprotection.\u003c\/em\u003e TUDCA crosses the blood-brain barrier and has been studied for its effects on dopaminergic neuron survival, amyloid-beta toxicity, and neuroinflammation. Research has explored its potential in models of Parkinson's disease, Alzheimer's disease, ALS, and stroke.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cem\u003eMetabolic health.\u003c\/em\u003e Landmark research published in Science demonstrated that TUDCA supplementation improved insulin sensitivity in obese humans, an effect attributed to its ability to reduce ER stress in both liver and muscle tissue. This makes TUDCA relevant not just for liver health but for blood sugar regulation and weight management.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cem\u003eAnti-inflammatory and antioxidant activity.\u003c\/em\u003e TUDCA suppresses NF-κB signalling, a master regulator of inflammatory gene expression, while scavenging reactive oxygen species (ROS). This dual action helps reduce chronic low-grade inflammation, one of the primary drivers of age-related decline.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eWho Uses TUDCA?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eTUDCA is used across a wide range of health and performance goals. People supporting liver health tend to use it, particularly those on high-protein diets, oral medications, or who consume alcohol regularly. Athletes and bodybuilders use it to maintain liver resilience during training cycles and supplementation. Longevity enthusiasts stack it with NMN, NAD+, resveratrol, and other longevity compounds. It's also popular among those with elevated liver enzymes as a complement to dietary and lifestyle interventions (always in consultation with a GP), and anyone interested in cellular health given TUDCA's broad cytoprotective and anti-inflammatory properties.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eTUDCA Dosage: How Much Should You Take?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eThe doses used in clinical studies range from 250mg to 1,750mg per day, depending on the condition being studied. For general liver support and longevity purposes, 500mg per day is the most widely used and well-tolerated dose, which is exactly what each Charava capsule provides. Take one capsule in the morning, with or before a meal.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eTUDCA vs UDCA: What's the Difference?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eUDCA (ursodeoxycholic acid) is the parent compound, a prescription-only medication used in clinical practice for primary biliary cholangitis and gallstones. TUDCA is its taurine-conjugated derivative, offering superior water solubility, better gut absorption, and more potent cytoprotective activity in research settings. For supplementation, TUDCA is the superior choice.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eWhy Buy TUDCA from Charava?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eNot all TUDCA supplements deliver what they promise. Each capsule contains 500mg of pharmaceutical-grade TUDCA, a full, research-consistent dose. Manufacturing is GMP-certified and independently audited to ISO 9001:2015 standards, with Certificates of Analysis available for full transparency on purity and potency. The formula is 100% vegan, using a plant-based hypromellose capsule with no animal-derived ingredients, no fillers, no binders, and no artificial additives. Charava also offers UK-based customer support and a subscribe and save option of up to 20%, with free gifts worth up to £141 on qualifying subscription orders.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eFrequently Asked Questions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cem\u003eIs TUDCA safe?\u003c\/em\u003e TUDCA has an extensive clinical safety profile and is generally well tolerated at doses up to 1,750mg per day in studies. The most commonly reported side effect at high doses is mild digestive discomfort. As with any supplement, consult your healthcare professional before use, especially if you are taking prescription medication or have a diagnosed liver condition.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cem\u003eHow long does TUDCA take to work?\u003c\/em\u003e Most people notice improvements in digestion and energy within one to two weeks. For liver enzyme markers and deeper cellular effects, measurable changes are typically seen after four to eight weeks of consistent daily use.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cem\u003eCan I take TUDCA with other supplements?\u003c\/em\u003e TUDCA combines well with NMN, NAD+, CoQ10, berberine, and other longevity and metabolic support supplements. There are no well-established negative interactions with common supplements. If you are on prescription medication, speak with your GP before stacking.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cem\u003eDo I need to cycle TUDCA?\u003c\/em\u003e No cycling is required. TUDCA is a naturally occurring bile acid and can be taken continuously. Many users take it as part of a daily long-term stack.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cem\u003eIs Charava's TUDCA vegan?\u003c\/em\u003e Yes. The capsule shell is made from hypromellose, a plant-derived alternative to standard gelatin capsules. The formula contains no animal-derived ingredients and no GMOs.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cem\u003eWhat is the difference between TUDCA and ox bile supplements?\u003c\/em\u003e Ox bile supplements contain a broad mixture of bile acids, of which TUDCA is only a small component. Supplementing with pure TUDCA gives you a precise, concentrated dose of the specific compound backed by the majority of clinical research.\u003c\/p\u003e","products":[{"product_id":"tudca-500mg","title":"Tudca 500mg","description":"\u003cp data-start=\"95\" data-end=\"495\" class=\"\"\u003eTUDCA (Tauroursodeoxycholic Acid) is a bile acid naturally produced in the body in small amounts. It plays a crucial role in supporting liver function, promoting bile flow, and protecting cells from stress and damage. TUDCA is especially valued for its liver-protective benefits, its role in cellular detoxification, and its growing reputation in the world of longevity, fitness, and performance.\u003c\/p\u003e\n\u003cp data-start=\"497\" data-end=\"750\" class=\"\"\u003eTUDCA supports mitochondrial health and has been studied for its potential neuroprotective effects. It is widely used by athletes, bodybuilders, and individuals on high-protein or supplement-heavy regimens to maintain liver health and metabolic balance.\u003c\/p\u003e\n\u003cp data-start=\"752\" data-end=\"778\" class=\"\"\u003e\u003cstrong data-start=\"752\" data-end=\"778\"\u003eTHE BENEFITS OF TUDCA\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli data-start=\"780\" data-end=\"922\"\u003e\n\u003cstrong\u003eSupports Liver Health \u003c\/strong\u003ePromotes healthy bile flow and liver detoxification, especially during times of stress or intense physical activity.\u003cbr\u003e\u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"780\" data-end=\"922\"\u003e\n\u003cstrong\u003eCellular Protection\u003c\/strong\u003e Acts as a cytoprotective agent to defend cells against oxidative and endoplasmic reticulum stress.\u003cbr\u003e\u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"780\" data-end=\"922\"\u003e\n\u003cstrong\u003eAntioxidant Action\u003c\/strong\u003e Helps neutralise oxidative stress and protects against free radical damage.\u003cbr\u003e\u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"780\" data-end=\"922\"\u003e\n\u003cstrong\u003eSupports Cholesterol \u0026amp; Metabolism\u003c\/strong\u003e May assist in maintaining healthy cholesterol levels and improving insulin sensitivity.\u003cbr\u003e\u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"780\" data-end=\"922\"\u003e\n\u003cstrong\u003eEnhances Recovery \u0026amp; Performance\u003c\/strong\u003e Popular among athletes and high-performance individuals for supporting recovery, liver resilience, and vitality.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong data-start=\"1423\" data-end=\"1442\"\u003eCHARAVA’S TUDCA\u003c\/strong\u003e delivers a high-quality, pharmaceutical-grade dose of tauroursodeoxycholic acid per capsule. It is also:\u003cbr\u003e\u003cstrong data-start=\"1549\" data-end=\"1574\"\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli data-start=\"1423\" data-end=\"1547\"\u003e\n\u003cstrong data-start=\"1549\" data-end=\"1574\"\u003eScientifically Backed \u003c\/strong\u003eFormulated using the latest research to maximise absorption and effectiveness.\u003cbr\u003e\u003cstrong data-start=\"1657\" data-end=\"1678\"\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"1423\" data-end=\"1547\"\u003e\n\u003cstrong data-start=\"1657\" data-end=\"1678\"\u003eRigorously Tested \u003c\/strong\u003eTested at every stage of production to ensure purity, potency, and safety.\u003cbr\u003e\u003cstrong data-start=\"1757\" data-end=\"1766\"\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"1423\" data-end=\"1547\"\u003e\n\u003cstrong data-start=\"1757\" data-end=\"1766\"\u003eVegan \u003c\/strong\u003eEncapsulated in plant-based capsules suitable for vegan and vegetarian diets.\u003cbr\u003e\u003cstrong data-start=\"1848\" data-end=\"1880\"\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"1423\" data-end=\"1547\"\u003e\n\u003cstrong data-start=\"1848\" data-end=\"1880\"\u003eFree from Unwanted Additives \u003c\/strong\u003eNo artificial colours, flavours, preservatives, gluten, soy, or GMOs—just clean, powerful liver support.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Charava","offers":[{"title":"30 Days","offer_id":47155166707926,"sku":"CHAR2072","price":29.99,"currency_code":"GBP","in_stock":true},{"title":"60 Days","offer_id":47155166740694,"sku":"CHAR2072-2","price":56.99,"currency_code":"GBP","in_stock":true},{"title":"90 Days","offer_id":47155166773462,"sku":"CHAR2072-3","price":80.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0617\/8039\/4198\/files\/tudca-500mg-8132850.png?v=1759349218"}],"url":"https:\/\/www.charava.co.uk\/collections\/tudca.oembed","provider":"Charava UK","version":"1.0","type":"link"}